The avenue stretches for about 3 kilometers (1.9 miles), connecting the Retiro and Constitución neighborhoods. It is lined with important landmarks, including the iconic Obelisk of Buenos Aires, which stands at its intersection with Corrientes Avenue, marking the city's historic and cultural epicenter. Other notable structures include the Teatro Colón, one of the world's foremost opera houses, and the Plaza de la República.
9 de Julio Avenue is also a major thoroughfare for vehicular traffic, featuring multiple lanes in each direction, as well as dedicated bus lanes to facilitate public transportation. The surrounding area is a vibrant mix of commercial, cultural, and governmental buildings, making it a hub of activity day and night. This avenue not only serves as a crucial transportation link but also as a scenic showcase of Buenos Aires' architectural and cultural heritage.